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BIOPROCESS DIGITAL PROFESSIONAL COURSES
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Design and cost evaluation of bioprocesses

Material balance, energy consumption, equipment sizing, investment and production cost, sensitivity and uncertainty analysis, cost reduction strategies

ONLINE COURSE: On-demand

COURSE FEE: 300 € per session 

COURSE ORGANIZATION

Course organized in 6 sessions

Scheduling: suggested one session per week

Effort: 4 - 8 hours per session

COURSE DESCRIPTION

The course teaches he basic methodology for the design and cost evaluation of bioprocess involving biotransformations, separation and thermal unit operations.

The guiding thread of the course is a virtual R&D project on the design and cost evaluation of an enzyme production process. The project objective is to design the most cost efficient process for the enzyme production by recombinant bacteria.

INSTRUCTOR​

  • Jean-Marc ENGASSER, BioProcess Digital

WHAT YOU'LL LEARN ​​

  • Evaluate the bioprocess materials consumption and effluents production, energy consumption and equipment sizes 

  • Determine the costs of materials, utilities, labor, equipment investment and utilization, and the overall bioprocess production cost 

  • Construct a spreadsheet simulator for bioprocess design and cost evaluation

  • Evaluate the uncertainty of the cost evaluation

  • Assess process modifications to reduce energy consumption and production cost

DIGITAL LEARNING​

  • Learning platform with course resources

  • Live or recorded slideshow videos

  • Fermentation project on spreadsheet templates with self-corrections and guides

  • Online collective or one-to-one tutoring

COURSE PROGRAM

SESSION 1: BIOPROCESS MATERIAL BALANCE 

Case study project: Enzyme production process by fermentation. Material balance of the process 

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SESSION 2: BIOPROCESS ENERGY CONSUMPTION

Mechanical and thermal energies consumption of the process equipment

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SESSION 3: EQUIPMENT SIZING

Sizing of the process equipment: tanks, fermentors, sterilizer, centrifuge, ultrafilter, spraydryer

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SESSION 4: INVESTMENT AND PRODUCTION COST

Investment cost of the production plant. Enzyme production cost: materials, energy, labor, equipment utilization

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SESSION 5: SENSITIVITY AND UNCERTAINTY ANALYSIS

Cost sensitivity analysis. Uncertainty of enzyme production cost

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SESSION 6: BIOPROCESS COST OPTIMIZATION

Bioprocess design modifications for energy saving and production cost reduction

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