BioProcess Digital Courses
BioProcess Digital Courses
BioProcess Digital Courses
BioProcess Digital Courses
BIOPROCESS DIGITAL PROFESSIONAL COURSES
en français
BIOPROCESS DIGITAL PROFESSIONAL COURSES
Introduction to microbial fermentation processes
Industrial fermentation processes. Microbial kinetics. Oxygen and CO2 in fermentors. Optimal operation of batch, continuous and fed-batch fermentations
ONLINE COURSE: On-demand
COURSE FEE: 300 € per session
COURSE ORGANIZATION
Course organized in 7 sessions
Sessions can be taken individually
Scheduling: suggested one session per week
Effort: 4 - 8 hours per session
COURSE DESCRIPTION
The course provides a comprehensive overview of industrial fermentation processes, including their technologies, operations, scale-up, and cost optimization. It reviews the kinetics of microbial transformations, the solubilities and transfer kinetics of oxygen and CO2. It provides in-depth insights into the optimal operations of batch, continuous, fed-batch, and high cell-density fermentations.
The course features a combination of methodological presentations and fermentation case studies.
INSTRUCTOR
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Jean-Marc Engasser, BioProcess Digital
DIGITAL LEARNING
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Learning platform with course resources
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Live or recorded slideshow presentations
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Case studies on spreadsheet templates with guides and corrections
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Online quizzes
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Online collective or one-to-one tutoring
COURSE PROGRAM
SESSION 1: INDUSTRIAL FERMENTATION PROCESSES
Microorganisms, media, products. Process operations. Fermentors technologies and operations. Fermentation costs
SESSION 2: MICROBIAL KINETICS
KInetic analysis in batch and continuous fermentors. Microbial kinetic laws. Industrial fermentations kinetics
SESSION 3: OXYGEN AND CO2 IN FERMENTORS
Fermentors aeration technologies. Solubilities and transfer kinetics. Determination of oxygen transfer coefficient
SESSION 4: BATCH FERMENTATIONS OPTIMAL OPERATIONS
Batch fermentations principles, kinetics and productivities. Optimization of anaerobic and aerobic fermentations
SESSION 5: CONTINUOUS FERMENTATIONS OPTIMAL OPERATIONS
Continuous fermentations principles. Dynamic and steady-state kinetics. Optimization of anaerobic and aerobic fermentations
SESSION 6: FED-BATCH FERMENTATIONS OPTIMAL OPERATIONS
Fed-batch fermentations principles, operation and kinetics. Optimization of fermentations for biomass and metabolites
SESSION 7: HIGH CELL-DENSITY FERMENTATIONS
Intensification by oxygen-enriched air. Perfusion fermentations with cell recycling. Limitations of high-density fermentations